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The participants had their blood pressure monitored for a day before beginning treatment and again after nine months of weekly tirzepatide injections. The results showed a significant decrease in the participants’ systolic blood pressure, the top number in blood pressure readings, which is a strong predictor of heart disease. It works similarly to semaglutide, the active compound in the weight loss drug Wegovy and its sister diabetes drug, Ozempic. Although there are effective blood pressure medications available, only about a quarter of people with hypertension have adequately controlled blood pressure, Hall said. He views the weight loss effect of the drug as a pleasant side effect that will make people more likely to take their medication.
Persons: , Eli Lilly, , Harlan Krumholz, Michael E, Wegovy, it’s, Ania Jastreboff, Hall, Krumholz, tirzepatide, Dr, Sanjay Gupta, CNN’s Meg Tirrell Organizations: CNN, American Heart Association, Food and Drug Administration, Yale University, Department of Medicine, University of Mississippi Medical Center, Yale Obesity Research Center, CNN Health Locations: United States
Maker of Wegovy, Ozempic showers money on U.S. obesity doctors
  + stars: | 2023-12-01 | by ( ) www.reuters.com   time to read: +23 min
Novo spent at least $25.8 million over the past decade on U.S. medical professionals to promote its two obesity drugs, Wegovy and Saxenda, the analysis found. Jastreboff has also worked on clinical trials of obesity drugs for Eli Lilly, which markets a Wegovy competitor. Some doctors said Novo’s payments exemplify how the flood of industry money can dominate decision-making about care and coverage. Government pharmacy officer Solaru said her agency concluded that the new obesity drugs could be cost-effective by preventing other weight-related diseases and boosting workplace productivity. In January, the personnel office told its health plans they must cover at least one GLP-1 obesity drug for 8 million workers, retirees and family members.
Persons: Lee Kaplan, Kaplan, , gastroenterologist, He’s, Novo, Donna Ryan, Ryan, , ” Kaplan, ” Novo, Robert Lustig, “ I’m, Lustig, They’re, Ania, ” Jastreboff, Jastreboff, Eli Lilly, Lilly’s Zepbound, Lilly, ” Lilly, Novo’s, Ayana, Sanders, Arthur Kellermann, ” Kellermann, mouthpieces, ’ ”, “ I'm, Jamy Ard, Ard, Dele, ” Solaru, ” Ryan, Scott Kahan, Kahan, Solaru, Christine Gallagher, Wegovy, Rebekah Carl, Carl, Jen Wexler, gaunt, Wexler Organizations: Novo Nordisk, Dartmouth, Nutrition Institute, Massachusetts General Hospital, Harvard Medical School, Reuters, Cambridge, Obesity Society, U.S ., Management, Reuters . Pharmaceutical, , U.S, United, National Health Service, University of California, U.S . Food, Drug Administration, Doctors, Wegovy’s, BMI, Yale University’s Center, Weight Management, Wall Street, American Medical Association, Rutgers University’s School of Public Health, Affordable, . Pharmaceutical, Companies, Uniformed Services University of Health Sciences, Wake Forest University, Wake Forest Baptist Health Weight Management, Obesity, Pennington Biomedical Research, U.S . National Institutes of Health, Personnel Management, Coalition, STOP, George Washington University, Novo Locations: CAMBRIDGE, Massachusetts, Boston, U.S, Novo, Danish, United States, Louisiana, San Francisco, Wegovy, Pennington, Baton Rouge , Louisiana, Government, New Columbia , Pennsylvania, Florida
HAVANA (AP) — Until recently, the space was the one-car garage of a private home in Cuba’s capital, Havana. Yet despite their modest setup, their prices are far from affordable, even for a doctor or a teacher, who make about 7,000 Cuban pesos a month (about $28 in the parallel market). Political Cartoons View All 1247 ImagesFor example, one kilo (2.2 pounds) of powdered milk from the Czech Republic costs 2,000 Cuban pesos (about $8). “I retired with 2,200 (Cuban pesos a month or $8.80) last year and I can’t even buy a package of chicken," she said. The novelty is that the small shops like the one in Vedado and bigger bodegas like the “Cuban Costco” are entirely private and accept payments in Cuban pesos.
Persons: ” Ania Espinosa, Espinosa, Ingracia Virgen Cruzata, , Goya, , Pedro Freyre, Akerman, That’s, Freyre Organizations: , Cuban Costco, Akerman Consulting, Miami Law School Locations: HAVANA, Cuba’s, Havana, El, Cuba, Cuban, Vedado, Czech Republic, U.S, Uruguay, Florida, America, Caribbean
To cardiologist Dr. Steven Nissen of the Cleveland Clinic, who wasn’t involved in the trial but is leading a similar one of tirzepatide, those effects are all evidence of the benefits of weight loss. Tirzepatide has shown greater levels of weight loss than semaglutide in clinical trials, leading many, including Nissen, to hope it will show even stronger cardiovascular benefits. Importantly, participants didn’t have a history of diabetes; a previous trial had shown that treating people with diabetes with a GLP-1 drug, Ozempic, reduced their cardiovascular risk. The Wegovy trial showed that 569 of 8,803 people taking the drug had a heart attack or stroke or died from heart-related causes, or 6.5%. The amount of weight loss seen in the trial, 9.4%, was less than in other studies of Wegovy, which showed average weight loss closer to 15%.
Persons: Ania Jastreboff, Wegovy, Dr, Amit Khera, National Institutes of Health’s Dr, Tiffany M, Powell, Wiley, Eli Lilly, Steven Nissen, wasn’t, ” Nissen, , Tirzepatide, Nissen, Michael Lincoff, Lincoff, , Jastreboff, Sanjay Gupta, hadn’t, “ semaglutide Organizations: CNN, Nordisk’s Wegovy, American Heart Association, Yale Obesity Research Center, University of Texas Southwestern Medical Center Dallas, National Institutes of Health’s, New England, of Medicine, US Food and Drug, Cleveland Clinic, Novo Nordisk, Cleveland, CNN Health Locations: Philadelphia, Powell
French retailers have criticised consumer goods giants like Unilever and Nestle for price hikes they say are unjustified. The government has also put pressure on the consumer goods makers to cut prices. "We should probably be able to demand that the big (consumer goods) groups cut prices by between 2% and 5%," he said. Consumer goods firms are likely to face increased pressure across Europe to cut prices, industry experts say. Lawmakers also asked about buying alliances, which some supermarkets use to negotiate prices jointly with peers at the European level, and whether they enable retailers to evade French regulations on pricing.
Persons: Sarah Meyssonnier, Les Mousquetaires, Thierry Cotillard, Cotillard, Mousquetaires, Jan, Alexandre Bompard, Lawmakers, Systeme, Dominique Schelcher, E Leclerc, Philippe Michaud, Miloud, Leclerc, Michaud, Helen Reid, Hugh Lawson Organizations: REUTERS, Unilever, Nestle, Carrefour, Senate, REWE, Thomson Locations: Carrefour, Montesson, Paris, France, Portugal, Spain, Europe, Greece, London
That’s the median weight loss experienced by people who take Wegovy, a drug from Novo Nordisk. Many patients started by taking Ozempic, a diabetes drug also by Novo Nordisk that led to weight loss as a side effect. Mounjaro, made by Eli Lilly and approved for treating diabetes, is expected to be approved soon for obesity. While price and insurance coverage pose problems for patients, health economists expect prices to come down as more drugs are approved and companies face competition. Medicare is forbidden by law to pay for weight-loss drugs, although there is an intense lobbying effort to change that.
Persons: Eli Lilly, David A, Eli Lilly’s, , , Ania, Robert F, Kushner Organizations: Novo Nordisk, Duke University, Yale University, Northwestern University Feinberg School of Medicine, Locations: Novo
Finance Minister Bruno Le Maire said on June 9 he had secured a pledge from 75 food companies to cut prices. French shoppers have paid more than 20% more for Nestle products each month since January versus last year, the data showed, and price increases peaked at 36.6% in May. Nestle, whose brands include Maggi stock cubes and Kit Kat chocolate bars, declined to comment. Similarly, stores sold products made by Activia yogurt owner Danone for between 11.2% and 16.7% more than last year in the first six months of the year. The NielsenIQ data shows the final prices retailers charge shoppers, and does not necessarily only reflect the prices food companies ask for from stores.
Persons: Arnd, Bruno Le Maire, Bernstein, Kat, Le Maire's, Jack Martin, Janus Henderson, Gaurav Gooptu, Richa Naidu, Sybille de La, Matt Scuffham, Sharon Singleton Organizations: Swiss, Nestle, REUTERS, Danone, Finance, Reuters, Reuters Graphics Reuters, Oberon Investments, U.S, Consumers, BNP, Thomson Locations: Bern, Konolfingen, Switzerland, France
Most analysts say what happened earlier isn't likely to spread across the banking sector and cause a full-blown meltdown. 'Banks are OK' — SVB and Signature were 'unique' failuresWhat happened at Silicon Valley Bank and Signature Bank could theoretically happen anywhere if depositors get worried enough about the safety of their money. Both banks catered to volatile industries that needed cash quickly — tech startups for SVB and crypto-related companies in the case of Signature. Nathan Stovall head of financial institutions research at S&P Global Market Intelligence"It was really those unique characteristics that led to those issues," says Nathan Stovall, head of financial institutions research at S&P Global Market Intelligence. Investors have since bid down shares of other banks — First Republic among them — whose profiles bear resemblance to SVB and Signature.
Resurgent inflation is devouring the income of Venezuelans - even the relatively privileged ones like Mendoza who have access to U.S. dollars. That is leaving them hungry and struggling to buy food and medicine, they told Reuters. "Neither dollars or bolivars are enough. Many Venezuelans were left to scour through garbage to find food, and millions fled the country to build new lives across South America and beyond. "Whether you pay in bolivars or dollars it is not enough," Lochunga said, sitting in front of his stall.
They have soared in popularity over the last year, in part from social media attention and billionaires like Elon Musk touting the drugs’ weight loss effects. Ozempic is not approved for weight loss, but doctors sometimes prescribe it off-label for that purpose. Harper took Ozempic off-label for weight loss from May until November (she paused while moving to Washington state but plans to start again). For Yazeed, weight loss was not the reason she went on Ozempic, nor was it a goal. He hasn't experienced side effects or weight loss from Ozempic, he said, but he recognizes that isn't true for everyone.
A recent experiment suggests that money can indeed buy happiness — at least for six months, among households making up to $123,000 a year. The group that got $10,000 reported higher levels of happiness than those who did not after their three months of spending. Then, after three more months had passed, the recipients still reported levels of happiness higher than when the experiment started. Ania Jaroszewicz, a behavioral scientist at Harvard University, said there is still no scientific consensus about whether money can buy happiness. Jaroszewicz highlighted that in any study of money and happiness, outcomes can also depend on the particular circumstances of people's lives and their expectations.
This week, Brandy Melville employees describe toxic conditions at the fast-fashion brand, and a French couple gives us an inside look at their sprawling Balinese villa. Plus, we have a glimpse into Phu Quoc, an island once hailed as Vietnam's "last paradise." PelotonPeloton is launching its own clothing brand, putting it in direct competition with Lululemon and Nike, brands it had previously partnered with. Andia / Contributor / Getty ImagesPhu Quoc was once hailed as Vietnam's "last paradise," with white-sand beaches and flourishing forest ecosystems. Take a look inside the sprawling villa.
Poate că acest lucru se datorează modului de funcționare și a simplității de a primi și de a consuma informația. Vorbim despre canalul de Telegram a fotografului Dumitru Vlah. Acolo vei găsi imagini care-ți vor bucura ochii, dar și istorii care le oferă a cestor imagini un suflu de viață. Doamna îi întinde încă o floricică în loc de rest, dar fata refuză și îi urează o zi bună. Ania nu este bolnavă; petele pe care le are pe tot corpul său o fac și mai specială, iar sufletul – mai frumos.
Persons: Dumitru Vlah, Ștefan cel Mare, Dumitru, Doamna, Ea, Groaznic Locations: Moldova, Mijloc
În ultima perioadă, devin tot mai populare conturile de Instagram, unde oamenii obișnuiți parodiază viața celebrităților mondiale. Deși, fotografiile vedetelor sunt frumoase, în realitate, instagramerii ne arată că este mai complicat să obții astfel de imagini, iar rezultatul acestora este diferit decât a starurilor și adesea amuzant. Ania Mohamed este o tânără din Moldova care încearcă pe contul ei de Instagram să facă astfel de parodii. Rihanna, Zendaya, Nicki Minaj, dar și alte vedete se regăsesc în lista fotografiilor publicate pe contul său. Vezi mai jos câteva imagini care îți arată că viața celebrităților în societatea noastră ar arăta altfel.
Persons: Mohamed, Rihanna Locations: Moldova, Zendaya
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